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Lp-PLA2 Native Protein

$90.00
24331302N
In stock
+

Minimum quantity for "Lp-PLA2 Native Protein" is 1.

Native Human Lp-PLA2 Antigen

Catalog No: 24331302N

Quantity: 0.1 mg

Description:

Gene ID:7941

Alternate Names: LDL-PLA2; LP-PLA2; PAFAD; PAFAF

Lipoprotein-associated phospholipase A2, also knownas platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45-kDaprotein of 441 amino acids. It is one of several PAF acetylhydrolases. Lp-PLA2is involved in the development of atherosclerosis, an observation that hasprompted interest as a possible therapeutic target (see, e.g. theinvestigational drug Darapladib). In human atherosclerotic lesions, 2 mainsources of Lp-PLA2 can be identified, including that which is brought into theintima bound to LDL (from the circulation), and that which is synthesized denovo by plaque inflammatory cells (macrophages, T cells, mast cells)."

It is used as a marker for cardiac disease.

Formulation: Liquid, supplied in PBS buffer, pH 8.0, containing 0.05%sodium azide.

Applications: Excellent for use as a control or calibrator.

Precaution: Sodium azide is a poisonous and hazardous substance whichshould be handled by trained staff only.

Certification: n/a.

Source:Human plasma.

Purity:95%

Concentration:

Fig 1. 1 ug ofpurified Lp-PLA2 protein on SDS-PAGE gel.

Storage & Stability: Stable at 4°C for shipping purposes and short term storage.

Upon receipt, store at -20°C.After reconstitution, store in working aliquots at -20°C to -80°C. Avoid repeatedfreeze-thaw cycles.

NOT FOR HUMAN USE. FOR RESEARCH ONLY. NOT FOR THERAPEUTICUSE.

>; l

ADX9043DA
$420.00

Mouse monoclonal Anti human Lp-PLA2 antibody, Protein G affinity purified.

In stock

Minimum quantity for "Lp-PLA2 Mouse Monoclonal Antibody, 100 ug (Cat# ADX9043DA)" is 1.


ADX9042CA
$420.00

Mouse monoclonal Anti human Lp-PLA2 antibody, Protein G affinity purified.

In stock

Minimum quantity for "Lp-PLA2 Mouse Monoclonal Antibody, 100 ug (Cat# ADX9042CA)" is 1.